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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH2
All Species:
12.1
Human Site:
S5
Identified Species:
22.18
UniProt:
O43255
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43255
NP_005058.3
324
34615
S5
_
_
_
M
S
R
P
S
S
T
G
P
S
A
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863586
282
31108
Cat
Felis silvestris
Mouse
Mus musculus
Q06986
325
34739
S6
_
_
M
S
R
P
S
S
T
G
P
S
A
N
K
Rat
Rattus norvegicus
Q8R4T2
325
34681
S6
_
_
M
S
R
P
S
S
T
G
P
S
A
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507643
433
47638
V117
T
K
R
T
E
E
A
V
K
N
F
G
E
R
T
Chicken
Gallus gallus
XP_426719
319
34023
S5
_
_
_
M
S
R
P
S
S
A
G
P
G
A
S
Frog
Xenopus laevis
Q9I8X5
313
34081
S5
_
_
_
M
S
R
P
S
S
A
G
P
C
A
S
Zebra Danio
Brachydanio rerio
Q7SYL3
331
34475
L14
A
G
G
A
A
G
G
L
G
A
G
K
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
I5
_
_
_
M
S
N
K
I
N
P
K
R
R
E
P
Honey Bee
Apis mellifera
XP_394284
279
30558
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
T15
A
V
S
T
I
S
G
T
A
V
L
G
K
T
M
Sea Urchin
Strong. purpuratus
XP_797311
281
31248
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STN8
327
36556
S10
T
D
S
M
E
C
V
S
S
T
G
N
E
I
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
70.6
N.A.
97.8
98.1
N.A.
56.5
91
85.8
76.1
N.A.
66.3
67.9
54.8
66.9
Protein Similarity:
100
N.A.
N.A.
78.4
N.A.
97.8
98.1
N.A.
63.9
93.5
88.2
82.4
N.A.
76.8
76.8
66.9
76.2
P-Site Identity:
100
N.A.
N.A.
0
N.A.
7.6
7.6
N.A.
0
75
75
6.6
N.A.
16.6
0
0
0
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
23
23
N.A.
0
83.3
83.3
33.3
N.A.
25
0
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
8
0
8
0
8
24
0
0
24
24
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
8
0
0
0
0
0
0
16
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
16
0
8
16
39
16
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
8
0
8
0
8
8
8
0
16
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
16
39
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
8
8
0
8
0
16
8
% N
% Pro:
0
0
0
0
0
16
24
0
0
8
16
24
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
16
24
0
0
0
0
0
8
8
8
0
% R
% Ser:
0
0
16
16
31
8
16
47
31
0
0
16
8
0
16
% S
% Thr:
16
0
0
16
0
0
0
8
16
16
0
0
0
8
8
% T
% Val:
0
8
0
0
0
0
8
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
47
47
31
0
0
0
0
0
0
0
0
0
0
0
0
% _